Learn about the different parts of the brain and their functions. Explore the brain and its functions through our interactive brain model videos. Learn about the cerebellum, parietal lobe, frontal lobe, temporal lobe, occipital lobe and brain stem.

  • Cerebellum
    The cerebellum controls movement. Voluntary muscle movements, posture and balance are controlled by the cerebellum. The cerebellum also regulates fine motor movement, like the skills used for painting a picture.
  • Brain Stem
    The brain stem controls most involuntary bodily functions that are vital to human existence such as heart rate, breathing, hunger and body temperature. Other fields that the brain stem controls are sensory feelings (such as hot or cold), involuntary movements of muscles, coughing and swallowing, among others.
  • Occipital Lobe
    The occipital lobe is responsible for vision. The occipital lobe receives and translates visual stimuli into meaningful data for the brain. The right occipital lobe analyzes visual information for the left visual field, and the left occipital lobe analyzes visual information for the right visual field.
  • Parietal Lobe
    The parietal lobe combines sensory information with a person’s memory to give meaning to objects. The parietal lobe is also responsible for spatial relations. It allows people to understand where their body is compared to objects around the person.
  • Frontal Lobe
    The frontal lobe is responsible for higher cognitive functions, like decision making. It regulates problem solving, memory, language, impulse control and emotions. The frontal lobe is also the home of consciousness, the “little voice in your head.”
  • Temporal Lobe
    The temporal lobes are responsible for memory, speech, learning and sense of smell. The right temporal lobe manages the recognition of faces and other visual objects. The left temporal lobe helps with remembering and understanding language, which is part of verbal memory. The back of the temporal lobe allows humans to recognize others’ emotions.

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INDICATIONS

GLIADEL Wafer (carmustine implant) is indicated in patients with newly diagnosed high-grade malignant glioma as an adjunct to surgery and radiation.

GLIADEL Wafer is also indicated in patients with recurrent glioblastoma multiforme as an adjunct to surgery.

IMPORTANT SAFETY INFORMATION

You should not be given GLIADEL Wafer if you are allergic to carmustine or any of the components of GLIADEL Wafer.

If you are undergoing surgery for malignant glioma and implantation of GLIADEL Wafer, you should be monitored closely for known complications, including convulsions, infections, abnormal wound healing, and swelling of the brain.

If you are pregnant or are planning to become pregnant, you should understand that carmustine, the active component of GLIADEL Wafer, can cause harm to the fetus if given to a pregnant woman. It is not known if either carmustine, or other components of GLIADEL Wafer are excreted in human milk. Many drugs are excreted in human milk and there is a risk for serious side effects from carmustine in nursing infants; therefore discontinuation of nursing is recommended if you will be receiving GLIADEL Wafer.

It is possible that if GLIADEL Wafers are not implanted properly, they could block the flow of cerebrospinal fluid and might cause abnormal accumulation of fluid in the brain (obstructive hydrocephalus).

The short-term and long-term safety of GLIADEL Wafer when given together with chemotherapy is not fully known.

Following surgery to remove a brain tumor and implantation of GLIADEL Wafer, the following side effects have been reported in clinical studies:

Seizures (convulsions): In clinical studies, seizures have occurred within days or several weeks following implantation of GLIADEL Wafer. Both new seizures and worsening of seizures have been reported.

Brain Swelling: Brain swelling has occurred in clinical studies. In some cases, brain swelling may require another surgery, and removal of GLIADEL Wafers or remnants of the wafers may be required.

Abnormal wound healing: In clinical studies, abnormal healing of the surgical wound has occurred following implantation of GLIADEL Wafer. These abnormalities included reopening of the surgical area, leaking of brain or spinal fluid, delays in healing, or other abnormalities in how the wound heals.

Brain Infections: In clinical studies, brain infections, including meningitis, have occurred following implantation of GLIADEL Wafer.

ADVERSE REACTIONS

Please read the full Prescribing Information and discuss it with your doctor or healthcare professional. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

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